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Explore antimicrobial resistance genes from the literature

traJ

TraJ protein

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to traJ

Browse AMR rules for traJ

Overview

Drug Classes: colistin
Organisms: Escherichia coli
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
-	A51G	-	Escherichia coli	colistin	Reslit	Candidate

Papers1

1

The evolution of infectious transmission promotes the persistence of mcr-1 plasmids.

PMID 37314200 · 2023

The A51G mutation in the 5'UTR of traJ enhances plasmid conjugation by reducing the inhibitory effect of FinP.

Mutation Information

Nucleotide Change: A51G
Organisms: Escherichia coli
Confers Resistance To: colistin
Validation Method: mutagenesis and plasmid transfer assays
Source Database: Reslit