trmD

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tRNA methyl transferase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

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UniProt

Protein entries specific to trmD

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Validation StatusCandidate

Overview

Mechanism: mutation leading to gentamicin resistance
Validation Method: genomic analysis
Drug Classes: gentamicin
Organisms: Staphylococcus aureus
Geographic Location: Taiwan
Papers: 1
Databases: Reslit

Papers1

A Comparative Phenotypic and Genomic Analysis of Methicillin-Resistant Staphylococcus aureus ST45 Isolates From Cellulitis and Osteomyelitis in Taiwan.

PMID 38409272 · 2024

The study identified specific mutations and gene acquisitions in OM-MRSA ST45 isolates that confer resistance to fluoroquinolones, fusidic acid, gentamicin, and doxycycline, highlighting their increased pathogenicity and resistance mechanisms compared to CL-MRSA ST45 isolates.

Gene Information

Gene Name: trmD
Allele: trmD
Encodes: tRNA methyl transferase
Source Database: Reslit
Mechanism: mutation leading to gentamicin resistance
Confers Resistance To: gentamicin
Organisms Tested In: • Staphylococcus aureus
Geographic Location: Taiwan
Validation Method: genomic analysis
Sequence Accession: PRJNA944816

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trmD

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trmD

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