Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
DNA helicase
Overview
Novel genetic determinants of low-level aminoglycoside resistance in Pseudomonas aeruginosa.
The study identifies multiple genes involved in low-level aminoglycoside resistance in Pseudomonas aeruginosa, highlighting the complexity of resistance mechanisms beyond traditional pathways.
A whole-genome screen identifies Salmonella enterica serovar Typhi genes involved in fluoroquinolone susceptibility.
The study identified several genes involved in fluoroquinolone susceptibility in Salmonella enterica serovar Typhi, including efflux pumps (acrA, acrB, tolC), regulatory genes (marA, phoP), and DNA repair genes (uvrD, xseA).
Pseudomonas aeruginosa heteroresistance to levofloxacin caused by upregulated expression of essential genes for DNA replication and repair.
The study identifies that upregulated expression of genes involved in DNA replication and repair, such as recA, uvrD, xseB, ssb, mutM, and crc, contributes to levofloxacin heteroresistance in Pseudomonas aeruginosa strains PAS71 and PAS81. Additionally, the expression of genes related to bacterial secretion systems, such as gspD, vgrG1, hcpC, clpV1, and ppkA, is increased in PAS81 under LVX stress.
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