Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
Van ligase;glycopeptide resistance gene cluster
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| vanC | Card DatabaseReference Gene CatalogReslit | 40 | VANCOMYCIN, vancomycin +1 | Enterococcus gallinarum +58 | Malaysia, Brazil, western Kansas, Spain, China, Egypt, Maputo, Mozambique, wastewater treatment plants|Canada, Northern Italy, South Africa, Australia, South Korea|Australia|America|The Netherlands|China, Bangladesh, Global, Indonesia, Edo State, Nigeria, Turkey, China|Xinjiang, United Arab Emirates, Beira, Mozambique|Mozambique, Europe, Europe|Spain|Netherlands, Kenya, Mayurbhanj, Odisha, India|India | 2003, 2007, 2009, 2012, 2013, 2016, 2018, 2019, 2020, 2021, 2022, 2024, 2025 | AF162694.1 | AAA24786.1 |
| vanC-2 | Reslit | 4 | vancomycin | Enterococcus casseliflavus +4 | Europe|North America|Asia, Brazil, China | 2002, 2004, 2018, 2023 | AY033089 | - |
| vanC-3 | Reslit | 1 | vancomycin | Enterococcus flavescens | Europe|North America|Asia | 2023 | - | - |
| vanC-2/3as | Reslit | 1 | vancomycin | Streptococcus spp. | North Upper Egypt|Egypt | 2021 | - | - |
Antimicrobial Resistance Mechanisms and Molecular Detection Techniques
The paper discusses molecular detection methods for antimicrobial resistance, focusing on genes like mecA and blaZ, which confer resistance to beta-lactam antibiotics in staphylococci.
Antimicrobial Resistance Mechanisms and Molecular Detection Techniques
The paper discusses molecular detection methods for antimicrobial resistance, focusing on genes like mecA and blaZ, which confer resistance to beta-lactam antibiotics in staphylococci.
Biochemical and genetic characterization of the vanC-2 vancomycin resistance gene cluster of Enterococcus casseliflavus ATCC 25788.
The study characterizes the vanC-2 gene cluster in Enterococcus casseliflavus ATCC 25788, identifying genes involved in vancomycin resistance, including vanC-2, vanXY C-2, vanT C-2, vanR C-2, and vanS C-2. These genes contribute to the production of cell wall precursors that replace d-alanine with d-serine, reducing vancomycin binding.
The vanC-3 vancomycin resistance gene cluster of Enterococcus flavescens CCM 439.
Antimicrobial resistance of Enterococcus sp. isolated from the intestinal tract of patients from a university hospital in Brazil.
The study identified vanC-1 and vanC-2 genes in Enterococcus gallinarum and Enterococcus casseliflavus, which confer resistance to vancomycin. These species showed intrinsic resistance to vancomycin, while other Enterococcus species exhibited varying levels of resistance to other antibiotics.
A nanoplex PCR assay for the rapid detection of vancomycin and bifunctional aminoglycoside resistance genes in Enterococcus species.
The study developed a nanoplex PCR assay for the simultaneous detection of vancomycin and bifunctional aminoglycoside resistance genes in Enterococcus species, including vanA, vanB, vanC, vanD, and aacA-aphD.
Genetic diversity of the low-level vancomycin resistance gene vanC-2/vanC-3 and identification of a novel vanC subtype (vanC-4) in Enterococcus casseliflavus.
Genetic diversity of the low-level vancomycin resistance gene vanC-2/vanC-3 and identification of a novel vanC subtype (vanC-4) in Enterococcus casseliflavus.
Genetic diversity of the low-level vancomycin resistance gene vanC-2/vanC-3 and identification of a novel vanC subtype (vanC-4) in Enterococcus casseliflavus.
Genetic diversity of the low-level vancomycin resistance gene vanC-2/vanC-3 and identification of a novel vanC subtype (vanC-4) in Enterococcus casseliflavus.
Genetic diversity of the low-level vancomycin resistance gene vanC-2/vanC-3 and identification of a novel vanC subtype (vanC-4) in Enterococcus casseliflavus.
Genetic diversity of the low-level vancomycin resistance gene vanC-2/vanC-3 and identification of a novel vanC subtype (vanC-4) in Enterococcus casseliflavus.
Genetic diversity of the low-level vancomycin resistance gene vanC-2/vanC-3 and identification of a novel vanC subtype (vanC-4) in Enterococcus casseliflavus.
Genetic diversity of the low-level vancomycin resistance gene vanC-2/vanC-3 and identification of a novel vanC subtype (vanC-4) in Enterococcus casseliflavus.
Risk factors for vancomycin-resistant enterococci colonisation in critically ill patients.
The study identifies vanC as a gene responsible for low-level vancomycin resistance in Enterococcus gallinarum and Enterococcus casseliflavus, highlighting its role in hospital settings.
Vancomycin-resistant gram-positive cocci isolated from the saliva of wild songbirds.
The study identified vancomycin-resistant gram-positive cocci, including Staphylococcus succinus, Staphylococcus saprophyticus, and Enterococcus gallinarum, carrying vanA, vanB, and vanC genes, indicating the presence of vancomycin resistance in wild songbirds.
Characterization of fecal vancomycin-resistant enterococci with acquired and intrinsic resistance mechanisms in wild animals, Spain.
The study identified a single VRE-a isolate from a wild boar carrying the vanA gene, which confers high-level resistance to vancomycin. Additionally, VRE-i isolates from red kites and white storks were found to have intrinsic resistance mechanisms via the vanC gene.
Genome Sequence of Riemerella anatipestifer Strain RCAD0122, a Multidrug-Resistant Isolate from Ducks.
The genome sequence of Riemerella anatipestifer strain RCAD0122 reveals the presence of nine types of antibiotic resistance-associated genes, including those encoding resistance to beta-lactams, fluoroquinolones, chloramphenicol, lincosamides, sulfonamides, aminoglycosides, tetracyclines, glycopeptides, and macrolides.
Metagenome and Metatranscriptome Analyses Using Protein Family Profiles.
The study demonstrates the utility of HMM-GRASPx for profiling antimicrobial resistance (AMR) gene families in metagenomic data sets, highlighting the distinct resistome profiles across different body sites and the importance of AMR gene abundance in understanding bacterial communities.
Dispersion of the Vancomycin Resistance Genes vanA and vanC of Enterococcus Isolated from Nile Tilapia on Retail Sale: A Public Health Hazard.
The study identified the vanC gene as a determinant of vancomycin resistance in Enterococcus isolates from Nile tilapia, highlighting the potential public health hazard posed by the dispersion of antibiotic-resistant bacteria through the food chain.
The complex resistomes of Paenibacillaceae reflect diverse antibiotic chemical ecologies.
The study explores the complex resistomes of Paenibacillaceae, revealing diverse antibiotic resistance mechanisms including intrinsic and acquired resistance genes such as aadD2, vanA, vanB, vanC, vanD, vanE, vanF, vanG, mcr, bla, tet, qnr, erm, mph, lnu, lsa, vat, vgb, cat, cfr, optrA, poxtA, sul, dfr, mexAB-OprM, acrAB-TolC, and oqxAB.
Molecular characteristics and comparative genomics analysis of a clinical Enterococcus casseliflavus with a resistance plasmid.
The study identified six resistance genes (aph3', ant6, bla, sat4, and two ermB) on the plasmid pEC369, along with a vanC-2 gene cluster on the chromosome, contributing to resistance against erythromycin, kanamycin, streptomycin, and vancomycin in Enterococcus casseliflavus EC369.
Gut carriage of antimicrobial resistance genes among young children in urban Maputo, Mozambique: Associations with enteric pathogen carriage and environmental risk factors.
The study identified several antimicrobial resistance genes (ARGs) in the gut of young children in urban Maputo, Mozambique, including aadA1, SHV, ermA, ermB, mefA, tetA, tetB, and others, which confer resistance to various antibiotics such as aminoglycosides, beta-lactams, macrolides, tetracyclines, and fluoroquinolones.
Comparative genomics of multidrug-resistant Enterococcus spp. isolated from wastewater treatment plants.
The study identified several AMR genes in multidrug-resistant Enterococcus spp. isolated from wastewater treatment plants, including vancomycin resistance genes (vanA, vanM, vanG, vanC), macrolide resistance genes (ermB, msrC), tetracycline resistance genes (tetL), aminoglycoside resistance genes (aad(6'), aac(6')-Ie-aph(2")-Ia, ant(9')-Ia, aph(3')-IIIa, SAT-4, ant(6')-Ia), chloramphenicol resistance gene (cat), dihydrofolate reductase genes (dfrE, dfrF, dfrG), and lincosamide resistance genes (InuB, InuG).
Defining the oral microbiome by whole-genome sequencing and resistome analysis: the complexity of the healthy picture.
The study characterizes the resistome of the healthy oral microbiome, identifying several resistance genes including mefA, ermB, tetB, aac1, SHV, QnrD, and msrA, which confer resistance to macrolides, tetracyclines, aminoglycosides, beta-lactams, and fluoroquinolones.
Complete Genomic Analysis of VRE From a Cattle Feedlot: Focus on 2 Antibiotic Resistance.
The study identified multiple antibiotic resistance genes in vancomycin-resistant enterococci (VRE) isolates from a cattle feedlot, including vanC1, vanC2/C3, vanXY-C, VanR, macA, macB, rlmA (II), erm(A), aac(6')-la, blaEC, tet(A), tet(L), S10p, gyrA, gyrB, msbA, S12p, rpoB, mdfA/cmr, liaF, liaR, liaS, bcrC, mprF, pgsA, ef-G, ef-TU, ddl, alr, kasA, isotRNA, inhA, fabl, murA, folA, and Dfr, which confer resistance to various antibiotics such as vancomycin, macrolides, aminoglycosides, β-lactams, tetracyclines, quinolones, and others.
Molecular characterization of Staphylococcus aureus isolated from hospital acquired sepsis in pediatrics, relation to antibiotics, resistance and virulence genes.
The study identified methicillin-resistant Staphylococcus aureus (MRSA) strains with high prevalence of mecA gene and reduced vancomycin susceptibility. No van genes were found, but the presence of fnBPA and PVL virulence genes was noted.
Antimicrobial Resistance in Porcine Enterococci in Australia and the Ramifications for Human Health.
The study identified antimicrobial resistance genes such as aac(6')-li, ermB, msrC, and vanC in porcine Enterococcus faecium isolates, highlighting the presence of resistance to aminoglycosides, macrolides, streptogramins, and glycopeptides.
New Insights into the Virulence Traits and Antibiotic Resistance of Enterococci Isolated from Diverse Probiotic Products.
The study identifies multiple antibiotic resistance genes, including msrC, lsaA, aac(6')-Ii, vanC, and tetM, in enterococci isolated from probiotic products, highlighting the potential risk of antimicrobial resistance and virulence factors in these isolates.
Subclinical Mastitis in Selected Bovine Dairy Herds in North Upper Egypt: Assessment of Prevalence, Causative Bacterial Pathogens, Antimicrobial Resistance and Virulence-Associated Genes.
The study identified several AMR genes in bacterial isolates from subclinical mastitis cases in bovine dairy herds in North Upper Egypt, including mecA, blaZ, icaD, aph(3')-IIIa, vanC-2/3as, hyl, cfb, tetA, sul1, fimH, and tsh. These genes were detected through PCR and are associated with resistance to methicillin, beta-lactams, aminoglycosides, vancomycin, tetracyclines, and sulphonamides.
Molecular detection of vancomycin and methicillin resistance in Staphylococcus aureus isolated from food processing environments.
The study identified methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant S. aureus (VRSA) in food processing environments in Bangladesh, highlighting the presence of resistance genes mecA, vanC, and blaTEM.
The resistomes of Mycobacteroides abscessus complex and their possible acquisition from horizontal gene transfer.
The study identifies numerous AMR genes in Mycobacteroides abscessus complex, highlighting the widespread presence of resistance to multiple antibiotic classes, including beta-lactams, aminoglycosides, glycopeptides, and others. Key findings include the detection of beta-lactamases like blaLAP-1 and blaTLA-2, 23S rRNA methyltransferases such as erm(33), erm(43), and erm(44), and various aminoglycoside modifying enzymes. Additionally, vancomycin resistance genes like vanA, vanB, and vanC were identified, along with efflux pump genes contributing to multidrug resistance.
Vancomycin Resistance in Enterococcus and Staphylococcus aureus.
The paper discusses the genetic basis of antibiotic resistance mechanisms in Enterococcus and Staphylococcus aureus, focusing on various resistance genes and mutations associated with glycopeptides, aminoglycosides, beta-lactams, macrolides, lincosamides, streptogramins, quinolones, tetracyclines, and fosfomycin.
Detection of Vancomycin Resistant Genes in Intrinsically Antibiotic Resistant Bacteria from the Gut Microbiota of Indonesian Individuals.
The study identified vancomycin-resistant genes (vanA, vanB, vanC, vanD, vanE, vanG) in intrinsically antibiotic-resistant bacteria from the gut microbiota of Indonesian individuals, highlighting the potential role of these bacteria in the spread of antibiotic resistance through horizontal gene transfer.
Characterization of resistance and virulence factors in livestock-associated methicillin-resistant Staphylococcus aureus.
The study identified several AMR genes including mecA, mecC, tetM, ermA, ermC, vanA, and vanC in livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) isolates. These genes conferred resistance to various antibiotics such as penicillin, tetracycline, erythromycin, and vancomycin. Additionally, virulence factors like PVL, tsst-1, icaA, and icaB were prevalent in the isolates.
Molecular characterization of resistance and biofilm genes of ESKAPE pathogens isolated from clinical samples: examination of the effect of boric acid on biofilm ability by cell culture method.
The study identified various AMR genes in ESKAPE pathogens, including vanA and vanC for vancomycin resistance, blaKPC and blaOXA-48 for carbapenem resistance, and others related to tetracycline, sulfonamide, quinolone, and aminoglycoside resistance. Additionally, biofilm-related genes such as icaA, icaD, gelE, asa1, and esp were detected in Staphylococcus and Enterococcus spp. Quorum sensing genes LasI and LasR were found in Pseudomonas aeruginosa, and biofilm production genes like mrkA, wbbM, wzm, and luxS were identified in Klebsiella pneumoniae.
Virulence and resistance gene analysis of Rothia nasimurium by whole gene sequencing.
The study identified multiple AMR genes in Rothia nasimurium Y1, including vanA, vanC, vanB, vanE, vanD, vanG, vanF, vanM, vanL, vanO, vanN, mtrA, vanRA, arlR, vanRI, vanRB, vanRC, vanRD, vanRF, vanRG, CpxR, kdpE, vanRM, vanRN, baeR, adeR, vanRL, smeR, gyrA, gyrB, parC, Mfd, mfd, PBP2, PBP2x, EF-Tu, dfrE, pncA, tetB(P), tetQ, tet44, tetT, tetW, tetS, tetM, tetO, otr(A), tet36, tet32, clbC, clbB, clbA, cipA, cfrA, cfrC, sul3, ParY, murA, cls, and ileS, which confer resistance to various antibiotics such as glycopeptides, beta-lactams, fluoroquinolones, tetracyclines, sulfonamides, aminoglycosides, lincosamides, phenicols, macrolides, and others.
Salad Vegetables as a Reservoir of Antimicrobial-Resistant Enterococcus: Exploring Diversity, Resistome, Virulence, and Plasmid Dynamics.
The study identified vancomycin resistance genes (vanC, vanXY-C2) in a vancomycin-susceptible E. faecalis isolate, along with optrA, tetM, ermB, lsa(A), msr(C), and ant(6)-Ia genes in Enterococcus isolates, highlighting the presence of multidrug-resistant strains in salad vegetables.
Multidrug-Resistant Staphylococcus aureus in Diabetic Foot Infections (DFI) from Beira, Mozambique: Prevalence and Virulence Profile.
The study identified high levels of multidrug resistance in Staphylococcus aureus isolates from diabetic foot infections in Beira, Mozambique, with resistance genes blaZ, mecA, vancA, vancB, ermB, ermC, dfrA, and dfrG being prevalent.
Genomic diversity in Porphyromonas: evidence of Porphyromonas catoniae commensality in lungs.
The study identified vancomycin resistance in Porphyromonas catoniae and clindamycin resistance in Porphyromonas uenonis, suggesting potential commensal behavior in the lung environment.
Comprehensive analysis of Enterococcus spp. from two European healthy infant cohorts shows stable genomic traits including antimicrobial resistance (AMR).
The study identified a range of antimicrobial resistance genes in Enterococcus spp. from two European infant cohorts, including aac(6')-aph(2"), vanC, and tet(M). These genes were associated with resistance to gentamicin, vancomycin, and tetracycline, respectively.
Diversity and antibiotic susceptibility profiles of bacterial isolates from wound infections in patients at the surgical unit of Kisii teaching and referral hospital, Kenya.
The study identified vanA, vanB, and vanC genes in Staphylococcus aureus and Staphylococcus xylosus isolates, indicating the presence of vancomycin resistance mechanisms in wound-infecting bacteria.
Diversity and antibiotic susceptibility profiles of bacterial isolates from wound infections in patients at the surgical unit of Kisii teaching and referral hospital, Kenya.
The study identified vanA, vanB, and vanC genes in Staphylococcus aureus and Staphylococcus xylosus isolates, indicating the presence of vancomycin resistance mechanisms in wound-infecting bacteria.
Unveiling community structure, antimicrobial resistance, and virulence factor of a wastewater sample of dairy farm located in mayurbhanj, odisha, india.
The study identified several antimicrobial resistance (AMR) genes in a dairy wastewater sample, including beta-lactamases, aminoglycoside acetyltransferases, tetracycline resistance proteins, quinolone resistance proteins, and macrolide ribosome methyltransferases. These genes were found in various bacterial species such as Escherichia coli, Staphylococcus aureus, Klebsiella pneumoniae, and Pseudomonas aeruginosa.
Sepsis secondary to postoperative Enterococcus gallinarum infection in a patient with rectal cancer: A case report.
Enterococcus gallinarum was isolated from wound secretion culture and showed intrinsic resistance to vancomycin, quinupristin/dalfopristin, trimethoprim, penicillin G, and ampicillin. The patient was treated with levofloxacin and meropenem, leading to clinical recovery.
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