Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
Van ligase;glycopeptide resistance gene cluster
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| vanM | Card Database | 1 | - | Enterococcus faecium | - | - | FJ349556.1 | ACL82961.1 |
| VanM | Card DatabaseReference Gene CatalogReslit | 14 | vancomycin, teicoplanin +2 | Enterococcus faecium +8 | China, Japan, wastewater treatment plants|Canada, Global, Guangdong province, China, Portugal, China|Xinjiang, Northern Italy, Europe | 2010, 2018, 2019, 2020, 2022, 2024, 2025 | FJ349556 | ACL82961.1 |
vanM, a new glycopeptide resistance gene cluster found in Enterococcus faecium.
The study identified a novel glycopeptide resistance gene cluster, vanM, in Enterococcus faecium, which confers resistance to vancomycin and teicoplanin.
vanM, a new glycopeptide resistance gene cluster found in Enterococcus faecium.
vanM, a new glycopeptide resistance gene cluster found in Enterococcus faecium.
Novel Multidrug-Resistant Enterococcal Mobile Linear Plasmid pELF1 Encoding vanA and vanM Gene Clusters From a Japanese Vancomycin-Resistant Enterococci Isolate.
The study identifies a novel multidrug-resistant enterococcal mobile linear plasmid pELF1 that encodes vanA and vanM gene clusters, conferring resistance to vancomycin, as well as other antibiotics such as streptomycin, streptothricin, kanamycin, and erythromycin.
Comparative genomics of multidrug-resistant Enterococcus spp. isolated from wastewater treatment plants.
The study identified several AMR genes in multidrug-resistant Enterococcus spp. isolated from wastewater treatment plants, including vancomycin resistance genes (vanA, vanM, vanG, vanC), macrolide resistance genes (ermB, msrC), tetracycline resistance genes (tetL), aminoglycoside resistance genes (aad(6'), aac(6')-Ie-aph(2")-Ia, ant(9')-Ia, aph(3')-IIIa, SAT-4, ant(6')-Ia), chloramphenicol resistance gene (cat), dihydrofolate reductase genes (dfrE, dfrF, dfrG), and lincosamide resistance genes (InuB, InuG).
The resistomes of Mycobacteroides abscessus complex and their possible acquisition from horizontal gene transfer.
The study identifies numerous AMR genes in Mycobacteroides abscessus complex, highlighting the widespread presence of resistance to multiple antibiotic classes, including beta-lactams, aminoglycosides, glycopeptides, and others. Key findings include the detection of beta-lactamases like blaLAP-1 and blaTLA-2, 23S rRNA methyltransferases such as erm(33), erm(43), and erm(44), and various aminoglycoside modifying enzymes. Additionally, vancomycin resistance genes like vanA, vanB, and vanC were identified, along with efflux pump genes contributing to multidrug resistance.
Vancomycin Resistance in Enterococcus and Staphylococcus aureus.
The paper discusses the genetic basis of antibiotic resistance mechanisms in Enterococcus and Staphylococcus aureus, focusing on various resistance genes and mutations associated with glycopeptides, aminoglycosides, beta-lactams, macrolides, lincosamides, streptogramins, quinolones, tetracyclines, and fosfomycin.
Vancomycin heteroresistance caused by unstable tandem amplifications of the vanM gene cluster on linear conjugative plasmids in a clinical Enterococcus faecium.
The study identifies vancomycin heteroresistance in a clinical Enterococcus faecium strain due to unstable tandem amplifications of the vanM gene cluster on linear conjugative plasmids.
Emergence and ongoing outbreak of ST80 vancomycin-resistant Enterococcus faecium in Guangdong province, China from 2021 to 2023: a multicenter, time-series and genomic epidemiological study.
The study identifies the emergence of a new vanA-harbouring plasmid in ST80 vancomycin-resistant Enterococcus faecium (VREfm) in Guangdong, China, contributing to an outbreak. The plasmid contains a vanA cassette embedded in a Tn1546-like structure and lacks conjugation-related genes, suggesting clonal transmission as the primary mode of spread.
Genetic basis of emerging vancomycin, linezolid, and daptomycin heteroresistance in a case of persistent Enterococcus faecium bacteremia.
The study identifies vanA and vanM operons as key determinants of glycopeptide resistance in Enterococcus faecium, along with rRNA and fabF mutations associated with linezolid and daptomycin resistance, respectively.
Clinical evaluation of a multiplex droplet digital PCR for diagnosing suspected bloodstream infections: a prospective study.
The study evaluated a multiplex droplet digital PCR (ddPCR) assay for diagnosing bloodstream infections, identifying key AMR genes such as bla KPC, bla NDM, bla VIM, bla IMP, bla OXA48, vanA, vanM, and mecA in clinical isolates.
Virulence and resistance gene analysis of Rothia nasimurium by whole gene sequencing.
The study identified multiple AMR genes in Rothia nasimurium Y1, including vanA, vanC, vanB, vanE, vanD, vanG, vanF, vanM, vanL, vanO, vanN, mtrA, vanRA, arlR, vanRI, vanRB, vanRC, vanRD, vanRF, vanRG, CpxR, kdpE, vanRM, vanRN, baeR, adeR, vanRL, smeR, gyrA, gyrB, parC, Mfd, mfd, PBP2, PBP2x, EF-Tu, dfrE, pncA, tetB(P), tetQ, tet44, tetT, tetW, tetS, tetM, tetO, otr(A), tet36, tet32, clbC, clbB, clbA, cipA, cfrA, cfrC, sul3, ParY, murA, cls, and ileS, which confer resistance to various antibiotics such as glycopeptides, beta-lactams, fluoroquinolones, tetracyclines, sulfonamides, aminoglycosides, lincosamides, phenicols, macrolides, and others.
Wild Birds as Drivers of Salmonella Braenderup and Multidrug Resistant Bacteria in Wetlands of Northern Italy.
The study identifies several AMR genes in bacterial isolates from wild aquatic birds in Northern Italy, including beta-lactamases (blaTEM, blaCMY-1, blaCMY-2, blaNDM, blaKPC), colistin resistance genes (mcr-2, mcr-3, mcr-4), tetracycline resistance genes (tetA, tetB, tetC, tetL, tetM, tetK), macrolide resistance genes (ermB, vatD, vgA, msrC), vancomycin resistance genes (vanC1, vanC2, vanM, vanG), sulfonamide resistance genes (sul1, sul2, sul3), aminoglycoside resistance genes (aac(3), aac(6')-Ib, aph(3')-Ia, armA, rmtB, rmtC, rmtF), and nitrofurantoin resistance genes (nfsA, nfsB).
Simultaneous and Accurate Visual Detection of Vancomycin-Resistant Enterococci vanA, vanB and vanM by Multiplex Recombinase Polymerase Amplification Combined with Lateral Flow Strip.
The study developed a multiplex RPA-LFS assay for the rapid and accurate detection of vanA, vanB, and vanM genes in vancomycin-resistant Enterococcus (VRE). The assay demonstrated high sensitivity and specificity, with 100% concordance with conventional PCR in clinical samples.
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