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Explore antimicrobial resistance genes from the literature

vanS-Cd

VanG-Cd-type vancomycin resistance histidine kinase VanS

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to vanS-Cd

Browse AMR rules for vanS-Cd

Validation StatusEstablished

Overview

Mechanism: VanG-Cd-type vancomycin resistance histidine kinase VanS
Drug Classes: VANCOMYCIN, vancomycin
Organisms: Clostridioides difficile
Papers: 3
Databases: Reference Gene Catalog
Mutations: 5

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
S333F	-	VanG-Cd-type vancomycin resistance histidine kinase VanS	Clostridioides difficile	vancomycin	Reference Gene Catalog	Candidate
R334H	-	VanG-Cd-type vancomycin resistance histidine kinase VanS	Clostridioides difficile	vancomycin	Reference Gene Catalog	Candidate
R334L	-	VanG-Cd-type vancomycin resistance histidine kinase VanS	Clostridioides difficile	vancomycin	Reference Gene Catalog	Candidate
G339D	-	VanG-Cd-type vancomycin resistance histidine kinase VanS	Clostridioides difficile	vancomycin	Reference Gene Catalog	Candidate
T369I	-	VanG-Cd-type vancomycin resistance histidine kinase VanS	Clostridioides difficile	vancomycin	Reference Gene Catalog	Candidate

Papers3

1

Gene Information

Gene Name: vanS-Cd
Allele: VanS
Encodes: VanG-Cd-type vancomycin resistance histidine kinase VanS
Source Database: Reference Gene Catalog
Confers Resistance To: VANCOMYCIN
Organisms Tested In: • Clostridioides difficile
Sequence Accession: CP011847.1
Protein Accession: AXB64455.1

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