Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
membrane-bound serine racemase
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| VanT | Reference Gene CatalogReslit | 18 | glycopeptides, VANCOMYCIN +2 | Enterococcus gallinarum BM4174 +16 | France|United Kingdom, Germany, British Columbia, Canada|British Columbia, global, Egypt, South Africa, Bangladesh, Mayurbhanj, Odisha, India|India, Europe | 2000, 2002, 2003, 2005, 2012, 2023, 2024, 2025 | AF162694 | AAK53980.1 |
| vanT C-2 | Reslit | 1 | vancomycin | Enterococcus casseliflavus ATCC 25788 | - | 2002 | AY033089 | - |
| vanTC | Reslit | 1 | glycopeptides | Streptococcus salivarius subsp. thermophilus | Europe|Southern and Western Ireland | 2019 | PRJEB35062 | - |
| van(T) | Reslit | 1 | glycopeptides | Lactobacillus reuteri +3 | Europe | 2025 | CP089115|CP089116|CP089117|CP089118 | - |
vanC cluster of vancomycin-resistant Enterococcus gallinarum BM4174.
The study identifies the vanC cluster in Enterococcus gallinarum BM4174, consisting of vanC-1, vanXY_C, vanT, vanR_C, and vanS_C. The genes vanC-1, vanXY_C, and vanT are necessary and sufficient for vancomycin resistance.
Biochemical and genetic characterization of the vanC-2 vancomycin resistance gene cluster of Enterococcus casseliflavus ATCC 25788.
The study characterizes the vanC-2 gene cluster in Enterococcus casseliflavus ATCC 25788, identifying genes involved in vancomycin resistance, including vanC-2, vanXY C-2, vanT C-2, vanR C-2, and vanS C-2. These genes contribute to the production of cell wall precursors that replace d-alanine with d-serine, reducing vancomycin binding.
Biochemical and genetic characterization of the vanC-2 vancomycin resistance gene cluster of Enterococcus casseliflavus ATCC 25788.
The vanC-3 vancomycin resistance gene cluster of Enterococcus flavescens CCM 439.
Transcriptional analysis of the vanC cluster from Enterococcus gallinarum strains with constitutive and inducible vancomycin resistance.
The study characterizes the vanC cluster in Enterococcus gallinarum strains with constitutive and inducible vancomycin resistance, identifying key genes and mutations involved in glycopeptide resistance mechanisms.
The purine-utilizing bacterium Clostridium acidurici 9a: a genome-guided metabolic reconsideration.
The study identifies genes in Clostridium acidurici 9a that confer resistance to bacitracin, acriflavine, and azaleucine.
Functional metagenomics reveals antibiotic resistance determinants in dairy-associated microbial communities
The study identified several antibiotic resistance (AR) determinants in dairy products and processing environments, including genes conferring resistance to beta-lactams, tetracyclines, glycopeptides, macrolides, and streptogramins. Notably, Lactococcus lactis was found to be a significant reservoir of multidrug-resistant genes.
Clostridioides difficile in South American Camelids in Germany: First Insights into Molecular and Genetic Characteristics and Antimicrobial Resistance.
The study identified several AMR genes and mutations in C. difficile isolates from South American camelids in Germany, including bla_CDD-1, vanZ1, aadE, tet(M), tet(40), vanG, vanR, vanS, vanT, and mutations in gyrA and gyrB associated with fluoroquinolone resistance.
Taxonomic Assignment-Based Genome Reconstruction from Apical Periodontal Metagenomes to Identify Antibiotic Resistance and Virulence Factors.
The study identified several antibiotic resistance genes (ARGs) in metagenomic assemblies from apical periodontal infections, highlighting the presence of multidrug resistance mechanisms in Enterobacter and Pseudomonas species.
Genomics of Tenacibaculum Species in British Columbia, Canada.
The study identified tetracycline resistance genes (tetQ, tetR) and vancomycin resistance genes (vanT, vanX, vanY) in various Tenacibaculum species isolated from Atlantic salmon in British Columbia, Canada.
Global Antimicrobial Resistance Gene Study of Helicobacter pylori: Comparison of Detection Tools, ARG and Efflux Pump Gene Analysis, Worldwide Epidemiological Distribution, and Information Related to the Antimicrobial-Resistant Phenotype.
The study identified 42 antimicrobial resistance genes (ARG) in Helicobacter pylori, including 16 related to single antibiotic class resistance and 26 related to multidrug resistance. Key genes include hp1181, copA, msbA, vanT, vanTr, mepA, and several RND efflux pumps. These genes were validated through multiple detection tools and curation processes.
Prioritization of Critical Factors for Surveillance of the Dissemination of Antibiotic Resistance in Pseudomonas aeruginosa: A Systematic Review.
The study identifies 25 critical mobile antibiotic resistance genes (ARGs) in Pseudomonas aeruginosa, including genes such as sul1, qacEΔ1, aac(6′)-Ib, bla VIM-1, and others, which are associated with various antibiotic classes and are linked to mobile genetic elements (MGEs).
Using 16S rDNA and metagenomic sequencing technology to analyze the fecal microbiome of children with avoidant/restrictive food intake disorder.
The study identified several antibiotic resistance genes in the fecal microbiome of children with ARFID, including vanT, tetQ, adeF, and ermF, with ermF showing significantly higher abundance in the ARFID group compared to healthy controls.
Resistome, mobilome, and virulome explored in clinical isolates derived from acne patients in Egypt: unveiling unique traits of an emerging coagulase-negative Staphylococcus pathogen.
The study identified multiple antibiotic resistance genes in coagulase-negative staphylococci (CoNS) isolates from acne patients in Egypt, including blaZ, mecA, tet(K), erm(C), lnuA, vgaA, dfrC, fusB, fosBx1, norA, and vanT. These genes were found to be located on plasmids and chromosomes, indicating a multidrug-resistant profile.
Genomic diversity, antibiotic resistance, and virulence in South African Enterococcus faecalis and Enterococcus lactis isolates.
The study identifies several antibiotic resistance genes in South African Enterococcus faecalis and Enterococcus lactis isolates, including dfrE, vanW, vanT, efrA, tet(M), AAC(6')-Ii, msrC, and vanY, which confer resistance to trimethoprim, glycopeptides, tetracycline, macrolides, and aminoglycosides.
Identification of pathways to high-level vancomycin resistance in Clostridioides difficile that incur high fitness costs in key pathogenicity traits.
The study identifies two pathways to high-level vancomycin resistance in Clostridioides difficile, involving mutations in vanT and dacS, which lead to modifications in the muropeptide terminal D-Ala-D-Ala and dysregulation of the dacJRS cluster, respectively.
Comprehensive genomic analysis reveals virulence and antibiotic resistance genes in a multidrug-resistant Bacillus cereus isolated from hospital wastewater in Bangladesh.
The study identified several AMR genes in a multidrug-resistant Bacillus cereus strain isolated from hospital wastewater, including beta-lactamases (BcII, BcIII, BcI), glycopeptide resistance genes (vanW, vanY, vanT), tetracycline resistance gene (tetB(P)), fosfomycin resistance gene (fosB), and efflux pump genes (bcrA, bcrB, ykkCD, qacJ).
Unveiling community structure, antimicrobial resistance, and virulence factor of a wastewater sample of dairy farm located in mayurbhanj, odisha, india.
The study identified several antimicrobial resistance (AMR) genes in a dairy wastewater sample, including beta-lactamases, aminoglycoside acetyltransferases, tetracycline resistance proteins, quinolone resistance proteins, and macrolide ribosome methyltransferases. These genes were found in various bacterial species such as Escherichia coli, Staphylococcus aureus, Klebsiella pneumoniae, and Pseudomonas aeruginosa.
Whole-Genome Sequence Analysis and Subtractive Screening of Lactobacilli in the Searching for New Probiotics to Protect the Mammary Glands.
The study identified the vanT gene in the vanG cluster, which confers glycopeptide resistance, and a bacitracin amidohydrolase gene in Ligilactobacillus salivarius 48, indicating potential resistance to vancomycin and bacitracin, respectively.
Whole-genome analysis of Lysinibacillus boronitolerans MSR1: A dairy-isolated multidrug-resistant and non-pathogenic strain.
The study identifies several antimicrobial resistance (AMR) genes in Lysinibacillus boronitolerans MSR1, including qacJ, vanW, vanT, and FosBx1, which confer resistance to disinfectants, vancomycin, and fosfomycin.
Genomic and Phenotypic Landscape of Antibiotic Resistance in Gut Lactic Acid Bacteria from Livestock Environments.
The study identified multiple antibiotic resistance genes in lactic acid bacteria (LAB) from livestock environments, including van(T), erm(B), cat(A), tet(W), lsa(D), arr, van(Y), and qac(G). These genes conferred resistance to various antibiotics, highlighting the potential for horizontal gene transfer and the importance of monitoring LAB for AMR.
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