vanrfs

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two-component regulatory system

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Validation StatusCandidate

Overview

Validation Method: sequencing and PCR analysis
Drug Classes: vancomycin
Organisms: Paenibacillus popilliae, Paenibacillus lentimorbus
Papers: 1
Databases: Reslit

Papers1

Putative VanRS-like two-component regulatory system associated with the inducible glycopeptide resistance cluster of Paenibacillus popilliae.

PMID 15980329 · 2005

The study identifies a putative glycopeptide resistance cluster in Paenibacillus popilliae, including the vanF gene encoding a d-Ala:d-Lac ligase and a VanRS-like two-component regulatory system, suggesting a mechanism for inducible vancomycin resistance.

Gene Information

Gene Name: vanrfs
Allele: vanRFS
Encodes: two-component regulatory system
Source Database: Reslit
Confers Resistance To: vancomycin
Organisms Tested In: • Paenibacillus popilliae
• Paenibacillus lentimorbus
Validation Method: sequencing and PCR analysis
Sequence Accession: AF155139|AF432144|AF098802

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vanrfs

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vanrfs

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