Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
antitoxin
Overview
| Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|
| T3N | - | enhanced cleavage by Lon protease | Escherichia coli | beta lactams | Reslit | Candidate |
| V5E | - | enhanced cleavage by Lon protease | Escherichia coli | beta lactams | Reslit | Candidate |
| L7P | - | enhanced cleavage by Lon protease | Escherichia coli | beta lactams | Reslit | Candidate |
| A13P | - | enhanced cleavage by Lon protease | Escherichia coli | beta lactams | Reslit | Candidate |
| L16R | - | enhanced cleavage by Lon protease | Escherichia coli | beta lactams | Reslit | Candidate |
| V20G | - | enhanced cleavage by Lon protease | Escherichia coli | beta lactams | Reslit | Candidate |
Shared mechanisms of enhanced plasmid maintenance and antibiotic tolerance mediated by the VapBC toxin:antitoxin system.
Mutations in VapB affect plasmid stability and antibiotic tolerance through enhanced cleavage by Lon protease.