Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
transporter protein
Overview
| Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|
| N25D | - | - | Streptococcus pneumoniae | vancomycin | Reslit | Candidate |
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| vex2 | Reslit | 1 | vancomycin | Streptococcus pneumoniae | Korea | 2006 | - | - |
| Vex2 | Reslit | 1 | vancomycin | Enterococcus faecium +1 | South Africa | 2024 | - | - |
Vancomycin-tolerant Streptococcus pneumoniae in Korea.
The study identified two vancomycin-tolerant Streptococcus pneumoniae strains, S3 and H8, with specific mutations in the vncS and vex2 genes that contribute to vancomycin tolerance.
Genome analysis of multidrug resistant Enterococcus faecium and Enterococcus faecalis circulating among hospitalized patients in uMgungundlovu District, KwaZulu-Natal, South Africa.
The study identified multiple AMR genes including VanC-1, VanG, Vex2, Vex3, emeA, Isa, ermB, TetM, fosB, ParC, ParE, gyrA, gyrB, MATE, MFS, and pmrA in multidrug-resistant Enterococcus faecium and Enterococcus faecalis. These genes conferred resistance to various antibiotics such as vancomycin, tetracycline, erythromycin, clindamycin, ciprofloxacin, and moxifloxacin.
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