vex3

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vancomycin tolerance

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UniProt

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Validation StatusCandidate

Overview

Validation Method: genomic analysis
Drug Classes: vancomycin
Organisms: Enterococcus faecium, Enterococcus faecalis
Geographic Location: South Africa
Papers: 1
Databases: Reslit

Papers1

Genome analysis of multidrug resistant Enterococcus faecium and Enterococcus faecalis circulating among hospitalized patients in uMgungundlovu District, KwaZulu-Natal, South Africa.

PMID 38965470 · 2024

The study identified multiple AMR genes including VanC-1, VanG, Vex2, Vex3, emeA, Isa, ermB, TetM, fosB, ParC, ParE, gyrA, gyrB, MATE, MFS, and pmrA in multidrug-resistant Enterococcus faecium and Enterococcus faecalis. These genes conferred resistance to various antibiotics such as vancomycin, tetracycline, erythromycin, clindamycin, ciprofloxacin, and moxifloxacin.

Gene Information

Gene Name: vex3
Allele: Vex3
Encodes: vancomycin tolerance
Source Database: Reslit
Confers Resistance To: vancomycin
Organisms Tested In: • Enterococcus faecium
• Enterococcus faecalis
Geographic Location: South Africa
Validation Method: genomic analysis

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vex3

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vex3

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