Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
RND efflux pump protein
Overview
Vibrio cholerae RND Family Efflux Systems Are Required for Antimicrobial Resistance, Optimal Virulence Factor Production, and Colonization of the Infant Mouse Small Intestine.
The study identifies VexB, VexD, and VexK as RND efflux systems in Vibrio cholerae that confer resistance to multiple antimicrobial compounds, including bile salts, detergents, and antibiotics. These efflux systems are crucial for optimal virulence factor production and colonization of the infant mouse small intestine.
The carRS-ompV-virK operon of Vibrio cholerae senses antimicrobial peptides and activates the expression of multiple resistance systems.
The study identifies ompV as a gene involved in polymyxin B resistance in Vibrio cholerae, showing that its deletion increases susceptibility to antimicrobial peptides.
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