Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
vga-type ABC-F protein
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| vgaE | Card DatabaseReslit | 3 | streptogramins, erythromycin +2 | Staphylococcus aureus subsp. aureus ST398 +2 | Lithuania, China | 2019, 2023 | FR772051.1 | CBY88983.1 |
| Scoh_vga(E) | Card Database | 1 | - | Staphylococcus cohnii | - | - | KF540226.1 | AHB37625.1 |
| Vga(E) | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 13 | CLINDAMYCIN, LINCOMYCIN +14 | Staphylococcus aureus subsp. aureus ST398 +13 | global, Switzerland, Denmark, Germany, Spain|Portugal|Germany|UK|Switzerland|Thailand|Italy | 2011, 2014, 2019, 2020, 2021, 2022, 2023 | FR772051.1 | CBY88983.1 |
| vga(E) | ResFinder Database | 1 | CLINDAMYCIN, LINCOMYCIN +4 | Staphylococcus aureus subsp. aureus ST398 | - | 2011 | FR772051 | - |
New transposon Tn6133 in methicillin-resistant Staphylococcus aureus ST398 contains vga(E), a novel streptogramin A, pleuromutilin, and lincosamide resistance gene.
New transposon Tn6133 in methicillin-resistant Staphylococcus aureus ST398 contains vga(E), a novel streptogramin A, pleuromutilin, and lincosamide resistance gene.
New transposon Tn6133 in methicillin-resistant Staphylococcus aureus ST398 contains vga(E), a novel streptogramin A, pleuromutilin, and lincosamide resistance gene.
New transposon Tn6133 in methicillin-resistant Staphylococcus aureus ST398 contains vga(E), a novel streptogramin A, pleuromutilin, and lincosamide resistance gene.
Identification of a novel vga(E) gene variant that confers resistance to pleuromutilins, lincosamides and streptogramin A antibiotics in staphylococci of porcine origin.
Identification of a novel vga(E) gene variant that confers resistance to pleuromutilins, lincosamides and streptogramin A antibiotics in staphylococci of porcine origin.
Antimicrobial Resistance in Staphylococci of Animal Origin
The paper discusses various antimicrobial resistance genes and mutations in staphylococci of animal origin, highlighting their roles in resistance to multiple antibiotics such as macrolides, lincosamides, streptogramins, oxazolidinones, and others. Key genes include erm, msr, mph, ere, lnu, vga, cfr, optrA, dfr, fus, ileS2, blaZ, aadD, ble, fosD, fosB, czrC, and qac genes, which confer resistance to specific antibiotics and are prevalent in different staphylococcal species.
Low Prevalence of Gram-Positive Isolates Showing Elevated Lefamulin MIC Results during the SENTRY Surveillance Program for 2015-2016 and Characterization of Resistance Mechanisms.
Draft Genome Sequence of Ciprofloxacin and Ceftriaxone Resistant Campylobacter jejuni MM26-781 Assigned to Novel ST Isolated From Common Pigeon in Lithuania.
The study identified several AMR genes and mutations in C. jejuni MM26-781, including blaOXA-448, gyrA, gyrB, rpoB, vgaE, cmeABC, and pmrA, along with mutations in gyrA, cmeR, and rpIV. These findings highlight the multidrug resistance profile of the isolate.
Methicillin-Resistant Staphylococcus aureus Strains in Swiss Pigs and Their Relation to Isolates from Farmers and Veterinarians.
The study identifies several AMR genes in MRSA strains from Swiss pigs, including aac(6')-aph(2"), dfrG, erm(A), erm(C), spc, str, tet(K), tet(M), and vga(E). These genes confer resistance to various antibiotics such as gentamicin, kanamycin, tobramycin, trimethoprim, erythromycin, clindamycin, lincomycin, streptogramin B, streptomycin, tetracycline, streptogramin A, pleuromutilin, and lincomycin.
Antimicrobial Resistance and Virulence Gene Profiles of Methicillin-Resistant and -Susceptible Staphylococcus aureus From Food Products in Denmark.
The study identified several antimicrobial resistance genes, including blaZ, tet(K), tet(L), tet(M), and various erm genes, in Staphylococcus aureus isolates from food products in Denmark. Additionally, the tst gene was detected in CC398 and CC45 isolates, indicating the presence of toxic shock syndrome toxin.
Antimicrobial resistance and virulence factors in livestock-associated MRSA from German dairy farms
The study identified various antimicrobial resistance genes in livestock-associated MRSA from German dairy farms, including mecA, fexA, tet(K), tet(M), vga(A), vga(E), dfrG, dfrK, aac(6')Ie-aph(2")Ia, str, spc, lsa(E), and erm(A). These genes conferred resistance to beta-lactams, chloramphenicol, tetracyclines, pleuromutilins, trimethoprim, aminoglycosides, streptomycin, spectinomycin, macrolides, lincosamides, and streptogramin B.
Farming Practice Influences Antimicrobial Resistance Burden of Non-Aureus Staphylococci in Pig Husbandries.
The study found that organic and alternative pig farming practices are associated with reduced antimicrobial resistance (AMR) in non-aureus staphylococci (NAS) compared to conventional farming. Specific AMR genes such as mecA, blaZ, blaPC1, and others were more prevalent in conventional farms, while organic farms showed lower levels of AMR genes for aminoglycosides, phenicols, and tetracyclines.
Genomic Diversity of Methicillin-Resistant Staphylococcus aureus CC398 Isolates Collected from Diseased Swine in the German National Resistance Monitoring Program GERM-Vet from 2007 to 2019.
The study identified numerous antimicrobial resistance (AMR) genes in methicillin-resistant Staphylococcus aureus (MRSA) CC398 isolates from diseased swine in Germany, including beta-lactam, tetracycline, macrolide, lincosamide, streptogramin B, phenicol, aminoglycoside, and fluoroquinolone resistance genes. These genes were often located on small transposons or plasmids, contributing to the multidrug resistance profile of the isolates.
Complete genome sequencing and comparative genomic analysis of three donkey Streptococcus equi subsp. equi isolates.
The study identified multiple antibiotic resistance genes in three donkey-derived Streptococcus equi subsp. equi isolates, including genes conferring resistance to beta-lactams, tetracyclines, macrolides, fluoroquinolones, and others. Notably, the HT1112 isolate showed resistance to six antimicrobials, while HTP133 and HTP232 showed resistance to fewer drugs. Additionally, the study highlighted the role of biofilm formation in antimicrobial resistance.
Antimicrobial Resistance in Coagulase-Negative Staphylococci: Resistome, Mobiloome, and Relatedness
The study identifies multiple AMR genes and mutations in CoNS isolates from various hosts, highlighting the spread of multidrug resistance and the role of mobile genetic elements in the dissemination of resistance traits.
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