vmh

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metallo-beta-lactamase fold metallohydrolase

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UniProt

Protein entries specific to vmh

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Validation StatusCandidate

Overview

Validation Method: overexpression and purification, kinetic analysis, mass spectrometry
Drug Classes: penicillin, cephalosporins, imipenem
Organisms: Vibrio vulnificus, Escherichia coli
Papers: 1
Databases: Reslit

Papers1

A Novel Cooperative Metallo-beta-lactamase Fold Metallohydrolase from Pathogen Vibrio vulnificus Exhibits β-Lactam Antibiotic-Degrading Activities.

PMID 34228542 · 2021

The study identifies and characterizes a novel metallo-beta-lactamase fold metallohydrolase (Vmh) from Vibrio vulnificus that exhibits broad-spectrum β-lactam antibiotic-degrading activities.

Gene Information

Gene Name: vmh
Allele: vmh
Encodes: metallo-beta-lactamase fold metallohydrolase
Source Database: Reslit
Confers Resistance To: penicillincephalosporinsimipenem
Organisms Tested In: • Vibrio vulnificus
• Escherichia coli
Validation Method: overexpression and purification, kinetic analysis, mass spectrometry
Sequence Accession: NZ_CP012882.1|AY567105

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vmh

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vmh

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