vqsM

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transcriptional regulator

NCBI Pathogen Isolates

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NCBI Reference Gene Catalog

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UniProt

Protein entries specific to vqsM

AMR Rules

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Validation StatusCandidate

Overview

Mechanism: directly binds to the nfxB promoter region and regulates its expression
Validation Method: EMSA, luciferase reporter assay, and MIC testing
Drug Classes: tetracycline, kanamycin
Organisms: Pseudomonas aeruginosa
Papers: 1
Databases: Reslit

Papers1

Molecular mechanisms of master regulator VqsM mediating quorum-sensing and antibiotic resistance in Pseudomonas aeruginosa.

PMID 25034696 · 2014

VqsM directly binds to the promoter regions of exsA and nfxB, regulating their expression and contributing to antibiotic resistance in Pseudomonas aeruginosa.

Gene Information

Gene Name: vqsM
Allele: vqsM
Encodes: transcriptional regulator
Source Database: Reslit
Mechanism: directly binds to the nfxB promoter region and regulates its expression
Confers Resistance To: tetracyclinekanamycin
Organisms Tested In: • Pseudomonas aeruginosa
Validation Method: EMSA, luciferase reporter assay, and MIC testing

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vqsM

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vqsM

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