waaI

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lipopolysaccharide biosynthesis protein

NCBI Pathogen Isolates

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UniProt

Protein entries specific to waaI

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Validation StatusCandidate

Overview

Mechanism: cell envelope modification
Validation Method: transposon insertion mutagenesis and MIC testing
Drug Classes: ciprofloxacin
Organisms: Salmonella enterica serovar Typhi
Papers: 1
Databases: Reslit

Papers1

A whole-genome screen identifies Salmonella enterica serovar Typhi genes involved in fluoroquinolone susceptibility.

PMID 32514543 · 2020

The study identified several genes involved in fluoroquinolone susceptibility in Salmonella enterica serovar Typhi, including efflux pumps (acrA, acrB, tolC), regulatory genes (marA, phoP), and DNA repair genes (uvrD, xseA).

Gene Information

Gene Name: waaI
Allele: waaI
Encodes: lipopolysaccharide biosynthesis protein
Source Database: Reslit
Mechanism: cell envelope modification
Confers Resistance To: ciprofloxacin
Organisms Tested In: • Salmonella enterica serovar Typhi
Validation Method: transposon insertion mutagenesis and MIC testing

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waaI

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waaI

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