Browse AMR Genes

Explore antimicrobial resistance genes from the literature

waaL

O-antigen ligase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to waaL

Browse AMR rules for waaL

Overview

Mechanism: increased vancomycin resistance
Drug Classes: vancomycin
Organisms: Escherichia coli
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
F332S	-	increased vancomycin resistance	Escherichia coli	vancomycin	Reslit	Candidate

Papers1

1

A mutant Escherichia coli that attaches peptidoglycan to lipopolysaccharide and displays cell wall on its surface.

PMID 25551294 · 2014

Mutation Information

Protein Change: F332S
Organisms: Escherichia coli
Confers Resistance To: vancomycin
Effect on Function: increased vancomycin resistance
Validation Method: mutant strain analysis and LPS modification
Source Database: Reslit