Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
B-band O-antigen polymerase
Overview
Decreased efficacy of antimicrobial agents in a polymicrobial environment.
The study identified mutations in the wzy gene, which encodes B-band O-antigen polymerase, as a novel mechanism of colistin resistance in P. aeruginosa. These mutations were found in both mono-species and polymicrobial cultures.
Efficacy of precisely tailored phage cocktails targeting carbapenem-resistant Acinetobacter baumannii reveals evolutionary trade-offs: a proof-of-concept study.
The study identifies mutations in the wzy gene of carbapenem-resistant Acinetobacter baumannii that contribute to phage resistance and altered capsule synthesis, leading to decreased virulence and increased antibiotic sensitivity.
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