ybtpq

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ABC transporter

NCBI Pathogen Isolates

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NCBI Reference Gene Catalog

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UniProt

Protein entries specific to ybtpq

AMR Rules

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Validation StatusCandidate

Overview

Mechanism: antimicrobial efflux
Validation Method: disk diffusion assay and MIC assay
Drug Classes: ceftazidime, erythromycin, streptomycin, rifampicin, tetracycline, imipenem, doxycycline, gentamicin, ofloxacin, novobiocin, polymyxin b, colistin
Organisms: Klebsiella pneumoniae, Escherichia coli
Papers: 1
Databases: Reslit

Papers1

A Virulence Associated Siderophore Importer Reduces Antimicrobial Susceptibility of Klebsiella pneumoniae.

PMID 33584611 · 2021

The yersiniabactin importer YbtPQ reduces antimicrobial susceptibility in Klebsiella pneumoniae and Escherichia coli by enhancing antimicrobial efflux, as evidenced by increased minimum inhibitory concentrations and zone of inhibition assays.

Gene Information

Gene Name: ybtpq
Allele: ybtPQ
Encodes: ABC transporter
Source Database: Reslit
Mechanism: antimicrobial efflux
Confers Resistance To: ceftazidimeerythromycinstreptomycinrifampicintetracyclineimipenemdoxycyclinegentamicinofloxacinnovobiocinpolymyxin bcolistin
Organisms Tested In: • Klebsiella pneumoniae
• Escherichia coli
Validation Method: disk diffusion assay and MIC assay
Sequence Accession: CP003200|NC_016845.1

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ybtpq

Gene Information

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ybtpq

Gene Information