ykcB

View on PubMed

Putative glycosyltransferase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to ykcB

AMR Rules

Browse AMR rules for ykcB

Validation StatusCandidate

Overview

Validation Method: Knockout of ykcB led to reduced susceptibility to vancomycin in B. subtilis, and complementation restored vancomycin tolerance.
Drug Classes: vancomycin
Organisms: Bacillus subtilis
Papers: 1
Databases: Reslit

Papers1

Knockout of ykcB, a Putative Glycosyltransferase, Leads to Reduced Susceptibility to Vancomycin in Bacillus subtilis.

PMID 36409129 · 2022

Knockout of ykcB, a putative glycosyltransferase, leads to reduced susceptibility to vancomycin in Bacillus subtilis. The ykcB knockout mutant exhibited increased virulence in silkworms, contrasting with vancomycin-resistant strains that typically show reduced virulence.

Gene Information

Gene Name: ykcB
Allele: ykcB
Encodes: Putative glycosyltransferase
Source Database: Reslit
Confers Resistance To: vancomycin
Organisms Tested In: • Bacillus subtilis
Validation Method: Knockout of ykcB led to reduced susceptibility to vancomycin in B. subtilis, and complementation restored vancomycin tolerance.

Comments (0)

No comments yet. Be the first to comment!

ykcB

Gene Information

Browse AMR Genes

ykcB

Gene Information