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yybT

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to yybT

Browse AMR rules for yybT

Overview

Mechanism: single resistance variant
Drug Classes: daptomycin
Organisms: Enterococcus faecalis
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
I440S	-	single resistance variant, cyclic dinucleotide phosphodiesterase YybT	Enterococcus faecalis	daptomycin	Card DatabaseReference Gene Catalog	Candidate

Papers1

1

Adaptation of Enterococcus faecalis to daptomycin reveals an ordered progression to resistance.

PMID 23959318 · 2013

Enterococcus faecalis YybT with mutation conferring daptomycin resistance; CARD accession: CARD:3003797

Mutation Information

Protein Change: I440S
Organisms: Enterococcus faecalis
Confers Resistance To: daptomycin
Effect on Function: single resistance variant
Source Database: Card Database