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yycF

response regulator

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to yycF

Browse AMR rules for yycF

Overview

Drug Classes: macrolides|lincosamides
Organisms: Staphylococcus aureus
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
E63K	G187A	-	Staphylococcus aureus	macrolides\|lincosamides	Reslit	Candidate

Papers1

1

Role in cell permeability of an essential two-component system in Staphylococcus aureus.

PMID 10368139 · 1999

The yycF1 mutation causes hypersensitivity to macrolides and lincosamides.

Mutation Information

yycF: p.E63K / c.G187A

Protein Change: E63K
Nucleotide Change: G187A
Organisms: Staphylococcus aureus
Confers Resistance To: macrolides|lincosamides
Validation Method: phenotypic characterization
Source Database: Reslit