Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
transcriptional regulator
Overview
| Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|
| V29G | overproduction of the AxyXY-OprZ efflux system | Achromobacter insuavis, Achromobacter xylosoxidans | tobramycin|amikacin|gentamicin|netilmicin|ceftazidime|cefepime|imipenem|meropenem|doripenem|ofloxacin|levofloxacin|ciprofloxacin|tetracycline|doxycycline|tigecycline|erythromycin | Reslit | Candidate |
Role of AxyZ Transcriptional Regulator in Overproduction of AxyXY-OprZ Multidrug Efflux System in Achromobacter Species Mutants Selected by Tobramycin.
The V29G mutation in AxyZ leads to overproduction of the AxyXY-OprZ efflux system, increasing resistance to multiple antibiotics.