Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
beta-lactamase
Overview
| Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|
| D179Y | - | confers resistance to ceftazidime/avibactam without loss of carbapenem resistance | Pseudomonas aeruginosa | ceftazidime avibactam | Reslit | Candidate |
Acquisition of resistance to ceftazidime-avibactam during infection treatment in Pseudomonas aeruginosa through D179Y mutation in one of two bla(KPC-2) gene copies without losing carbapenem resistance.
The D179Y mutation in one of the two bla(KPC-2) gene copies leads to resistance to ceftazidime/avibactam without loss of carbapenem resistance.