Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
delamanid resistance
Overview
Genomic analysis of Mycobacterium tuberculosis variant bovis strains isolated from bovine in the state of Mato Grosso, Brazil.
The study identified multiple AMR genes and mutations in Mycobacterium tuberculosis variant bovis strains from Mato Grosso, Brazil, including resistance to pyrazinamide, isoniazid, rifampicin, streptomycin, ethambutol, ethionamide, fluoroquinolones, kanamycin, capreomycin, paraminosalicylic acid, cycloserine, bedaquiline, linezolid, and delamanid.
Selection of Multi-Drug Targets against Drug-Resistant Mycobacterium tuberculosis XDR1219 Using the Hyperbolic Mapping of the Protein Interaction Network.
The study identifies several drug targets (DTs) in Mycobacterium tuberculosis XDR1219 using hyperbolic mapping of the protein interaction network. Key DTs include rpsA, rpsL, embB, embA, fbiC, fbiB, rpoB, dnaK, rpoA, rpoC, rpoZ, ddl, alr, pbpB, rplD, rplC, rmlC, Isr2, tlyA, pknB, dprE1, fas, accD1, accE5, Rv0200, galE3, pks5, msl3, phoP, dacB2, pknI, echA19, ltp3, and Rv3520c, which are involved in various metabolic pathways and are targeted by different antibiotics.
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