ResLit - Antimicrobial Resistance Gene & Mutation Database

GenefbiB

delamanid resistance

Protein ChangeK448R

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: delamanid|pretomanid, delamanid
Organisms: Mycobacterium tuberculosis
Papers: 2

Paper Information2

Genetic diversity of candidate loci linked to Mycobacterium tuberculosis resistance to bedaquiline, delamanid and pretomanid.

PMID 34593898 · 2021

associated with increased MICs

Mutation Information

fbiB: p.K448R

Protein Change: K448R
Organisms: Mycobacterium tuberculosis
Confers Resistance To: delamanid|pretomanid
Validation Method: mutational analysis
Source Database: Reslit

High clustering rate and genotypic drug-susceptibility screening for the newly recommended anti-tuberculosis drugs among global extensively drug-resistant Mycobacterium tuberculosis isolates.

PMID 35792049 · 2022

Mutation Information

fbiB: p.K448R

Protein Change: K448R
Confers Resistance To: delamanid
Validation Method: genotypic drug-susceptibility test
Source Database: Reslit

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