rho

transcriptional termination factor

Overview

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
S153F	-	-	-	tetracycline	Reslit	Candidate
G56C	-	reduces susceptibility to cefuroxime by impairing RNA binding	Bacillus subtilis	cefuroxime	Reslit	Candidate

Papers2

Complex chromosomal neighborhood effects determine the adaptive potential of a gene under selection.

mutations in rho enable read-through transcription into tetA-yfp

Mutations in the Primary Sigma Factor σA and Termination Factor Rho That Reduce Susceptibility to Cell Wall Antibiotics.

The rho G56C mutation reduces susceptibility to cefuroxime by impairing RNA binding.

Protein Change: G56C
Organisms: Bacillus subtilis
Confers Resistance To: cefuroxime
Effect on Function: reduces susceptibility to cefuroxime by impairing RNA binding
Validation Method: genetic reconstruction and MIC assays
Source Database: Reslit