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Browse Mutations dfrCH149R

GenedfrC

Trimethoprim resistance protein

Protein ChangeH149R

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: trimethoprim
Papers: 1

Paper Information1

1

Antistaphylococcal activity of dihydrophthalazine antifolates, a family of novel antibacterial drugs.

PMID 19188385 · 2009

Multiple mutations in dfr(C) lead to trimethoprim resistance.

Mutation Information

Protein Change: H149R
Confers Resistance To: trimethoprim
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research