ResLit - Antimicrobial Resistance Gene & Mutation Database

GeneporB1b

outer membrane porin

Protein ChangeG120N

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: penicillin|tetracycline, ceftriaxone|cefixime
Organisms: Neisseria gonorrhoeae
Papers: 2

Paper Information2

Predominant porB1A and porB1B genotypes and correlation of gene mutations with drug resistance in Neisseria gonorrhoeae isolates in Eastern China.

PMID 21067570 · 2010

Deletions at A121 and N122 show the highest resistance.

Mutation Information

porB1b: p.G120N

Protein Change: G120N
Organisms: Neisseria gonorrhoeae
Confers Resistance To: penicillin|tetracycline
Validation Method: drug sensitivity test
Source Database: Reslit

The antimicrobial resistance landscape of Neisseria gonorrhoeae in New Zealand from November 2018 to March 2019 and the role of sexual orientation in transmission.

PMID 34755593 · 2021

Mutations in porB1b contribute to reduced susceptibility to ceftriaxone and cefixime.

Mutation Information

porB1b: p.G120N

Protein Change: G120N
Organisms: Neisseria gonorrhoeae
Confers Resistance To: ceftriaxone|cefixime
Validation Method: gene detection and MIC testing
Source Database: Reslit

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