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Browse Mutations sarAC27T

GenesarA

Nucleotide ChangeC27T

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: vancomycin
Organisms: Staphylococcus aureus
Papers: 1

Paper Information1

1

Protein cysteine phosphorylation of SarA/MgrA family transcriptional regulators mediates bacterial virulence and antibiotic resistance.

PMID 22927394 · 2012

Mutation of Cys-9 to Ser in SarA enhances hemolysis and reduces vancomycin susceptibility.

Mutation Information

Nucleotide Change: C27T
Organisms: Staphylococcus aureus
Confers Resistance To: vancomycin
Validation Method: mutant protein expression and EMSA
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research