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Browse Mutations mepAD183A

GenemepA

MATE family efflux pump

Protein ChangeD183A

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: down function
Resistance To: fluoroquinolones
Organisms: Staphylococcus aureus
Papers: 1

Paper Information1

1

Mutagenesis and modeling to predict structural and functional characteristics of the Staphylococcus aureus MepA multidrug efflux pump.

PMID 23175649 · 2013

Mutations in mepA were identified through gradient plate experiments and site-directed mutagenesis.

Mutation Information

Protein Change: D183A
Organisms: Staphylococcus aureus
Confers Resistance To: fluoroquinolones
Effect on Function: down function
Validation Method: susceptibility testing, ethidium efflux quantification
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research