ResLit - Antimicrobial Resistance Gene & Mutation Database

GenemecC

alternative penicillin-binding protein 2a

Protein ChangeF443L

Nucleotide ChangeT1327C

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: oxacillin
Organisms: Staphylococcus aureus
Papers: 1

Paper Information1

Full-Genome Sequencing Identifies in the Genetic Background Several Determinants That Modulate the Resistance Phenotype in Methicillin-Resistant Staphylococcus aureus Strains Carrying the Novel mecC Gene.

PMID 28069659 · 2017

Mutation Information

mecC: p.F443L / c.T1327C

Protein Change: F443L
Nucleotide Change: T1327C
Organisms: Staphylococcus aureus
Confers Resistance To: oxacillin
Validation Method: Sanger sequencing and functional testing
Source Database: Reslit

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