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Browse Mutations oprDG123A

GeneoprD

porin

Nucleotide ChangeG123A

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: loss_of_function
Resistance To: meropenem
Organisms: Pseudomonas aeruginosa
Papers: 1

Paper Information1

1

Rapid evolution and host immunity drive the rise and fall of carbapenem resistance during an acute Pseudomonas aeruginosa infection.

PMID 33911082 · 2021

Mutations in oprD lead to carbapenem resistance.

Mutation Information

Nucleotide Change: G123A
Organisms: Pseudomonas aeruginosa
Confers Resistance To: meropenem
Effect on Function: loss_of_function
Validation Method: MIC testing
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research