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Browse Mutations ompFG120D

GeneompF

outer membrane porin

Protein ChangeG120D

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: increased permeation of various substrates, including carbohydrates and antibiotics
Resistance To: tetracycline|enoxacin
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

Role of internal loop dynamics in antibiotic permeability of outer membrane porins.

PMID 35193963 · 2022

Mutations in ompF were found to alter permeability of antibiotics.

Mutation Information

Protein Change: G120D
Organisms: Escherichia coli
Confers Resistance To: tetracycline|enoxacin
Effect on Function: increased permeation of various substrates, including carbohydrates and antibiotics
Validation Method: whole-cell accumulation assay
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research