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Browse Mutations acnA3608fs

GeneacnA

aconitate hydratase

Nucleotide Change3608fs

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: partially restored antimicrobial susceptibility
Resistance To: fluoroquinolones|ceftazidime
Organisms: Stenotrophomonas maltophilia
Papers: 1

Paper Information1

1

Acquired resistance of Stenotrophomonas maltophilia to antimicrobials induced by herbicide paraquat dichloride.

PMID 39196988 · 2024

Frameshift mutation in acnA leads to partial restoration of antimicrobial susceptibility upon complementation.

Mutation Information

Nucleotide Change: 3608fs
Organisms: Stenotrophomonas maltophilia
Confers Resistance To: fluoroquinolones|ceftazidime
Effect on Function: partially restored antimicrobial susceptibility
Validation Method: complementation assay
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research