ResLit - Antimicrobial Resistance Gene & Mutation Database

GenecrrB

Enzyme IICBGlc

Protein ChangeA200Y

Nucleotide ChangeG600A

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: colistin
Organisms: Klebsiella pneumoniae
Papers: 1

Paper Information1

Efficacy of colistin-based combinations against pandrug-resistant whole-genome-sequenced Klebsiella pneumoniae isolated from hospitalized patients in Egypt: an in vitro/vivo comparative study.

PMID 39627871 · 2024

Amino acid substitution in the histidine kinase domain

Mutation Information

crrB: p.A200Y / c.G600A

Protein Change: A200Y
Nucleotide Change: G600A
Organisms: Klebsiella pneumoniae
Confers Resistance To: colistin
Validation Method: whole-genome sequencing and functional analysis
Source Database: Reslit

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