ResLit - Antimicrobial Resistance Gene & Mutation Database

GenerpsJ

Protein ChangeT39R

Nucleotide ChangeC117G

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: tigecycline
Papers: 1

Paper Information1

Emergence of Tigecycline-Nonsusceptible Carbapenem-Resistant Klebsiella pneumoniae with Metallo-β-Lactamase and Transferable Ceftazidime-Avibactam Resistance in China.

PMID 40137738 · 2025

mutation reduces tigecycline susceptibility

Mutation Information

rpsJ: p.T39R / c.C117G

Protein Change: T39R
Nucleotide Change: C117G
Confers Resistance To: tigecycline
Validation Method: mutagenesis and MIC testing
Source Database: Reslit

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