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Browse Mutations pbp3I332V

Genepbp3

penicillin-binding protein

Protein ChangeI332V

Nucleotide ChangeATC->GTC

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: ceftazidime
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

Potential role of avibactam in restoring susceptibility in Escherichia coli with two copies of bla(KPC-3) and PBP3 mutations.

PMID 40595049 · 2025

Mutations in PBP3 were associated with increased ceftazidime MICs.

Mutation Information

pbp3: p.I332V / c.ATC->GTC

Protein Change: I332V
Nucleotide Change: ATC->GTC
Organisms: Escherichia coli
Confers Resistance To: ceftazidime
Validation Method: whole-genome variant calling
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research