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Browse Mutations mrcAG414D

GenemrcA

penicillin-binding protein

Protein ChangeG414D

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: cefiderocol
Organisms: E. coli
Papers: 1

Paper Information1

1

Mechanisms of Cefiderocol Resistance in Carbapenemase-Producing Enterobacterales: Insights from Comparative Genomics.

PMID 40724005 · 2025

mutated gene associated with reduced cefiderocol susceptibility

Mutation Information

Protein Change: G414D
Organisms: E. coli
Confers Resistance To: cefiderocol
Validation Method: structural modeling
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research