ResLit - Antimicrobial Resistance Gene & Mutation Database

Genepbp2a

penicillin-binding protein

Protein ChangeG246E

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: ceftaroline
Organisms: Staphylococcus aureus
Papers: 1

Paper Information1

Missense mutations in PBP2A Affecting Ceftaroline Susceptibility Detected in Epidemic Hospital-Acquired Methicillin-Resistant Staphylococcus aureus Clonotypes ST228 and ST247 in Western Switzerland Archived since 1998.

PMID 25583724 · 2015

Detected in strains with increased ceftaroline MIC

Mutation Information

pbp2a: p.G246E

Protein Change: G246E
Organisms: Staphylococcus aureus
Confers Resistance To: ceftaroline
Validation Method: sequencing and susceptibility testing
Source Database: Reslit

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