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Browse Mutations panDM117I

GenepanD

aspartate decarboxylase

Protein ChangeM117I

Validation StatusConfirmed2+ DBs

Databases

ResFinder DatabaseReslit

Overview

Resistance To: pyrazinamide
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

1

Aspartate decarboxylase (PanD) as a new target of pyrazinamide in Mycobacterium tuberculosis.

PMID 26038753 · 2014

All mutations occur in the C-terminus of the PanD protein.

Mutation Information

Protein Change: M117I
Organisms: Mycobacterium tuberculosis
Confers Resistance To: pyrazinamide
Validation Method: whole-genome sequencing and susceptibility testing
Source Database: ReslitResFinder Database

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research