ResLit - Antimicrobial Resistance Gene & Mutation Database

GeneadeS

sensor kinase

Protein ChangeA130V

Nucleotide ChangeC390T

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: tigecycline
Organisms: Acinetobacter baumannii
Papers: 1

Paper Information1

Acinetobacter baumannii Repeatedly Evolves a Hypermutator Phenotype in Response to Tigecycline That Effectively Surveys Evolutionary Trajectories to Resistance.

PMID 26488727 · 2015

Mutation Information

adeS: p.A130V / c.C390T

Protein Change: A130V
Nucleotide Change: C390T
Organisms: Acinetobacter baumannii
Confers Resistance To: tigecycline
Validation Method: Phenotypic assays and whole genome sequencing
Source Database: Reslit

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