ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeW483G

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: rifampicin
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

Compensatory Mutations of Rifampin Resistance Are Associated with Transmission of Multidrug-Resistant Mycobacterium tuberculosis Beijing Genotype Strains in China.

PMID 26902762 · 2016

The rpoC W483G mutation was found in isolates with rpoB S531L mutations and was associated with increased transmission.

Mutation Information

rpoC: p.W483G

Protein Change: W483G
Organisms: Mycobacterium tuberculosis
Confers Resistance To: rifampicin
Validation Method: sequencing and correlation with resistance profiles
Source Database: Reslit

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