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Browse Mutations pbp2xH438Y

penicillin-binding protein 2X

Protein ChangeH438Y

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: substitutions in PBP2X are associated with penicillin non-susceptibility
Resistance To: penicillin
Organisms: Streptococcus agalactiae
Papers: 1

Paper Information1

1

Heterogeneity of penicillin-non-susceptible group B streptococci isolated from a single patient in Germany.

PMID 31740946 · 2020

Substitutions in PBP2X are associated with penicillin non-susceptibility.

Mutation Information

Protein Change: H438Y
Organisms: Streptococcus agalactiae
Confers Resistance To: penicillin
Effect on Function: substitutions in PBP2X are associated with penicillin non-susceptibility
Validation Method: genomic analysis
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research