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Browse Mutations ddnW20*

Geneddn

delphi-like domain-containing protein

Protein ChangeW20*

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: delamanid|pretomanid
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

1

The ddn Trp20Stop Mutation and Its Association with Lineage 4.5 and Resistance to Delamanid and Pretomanid in Mycobacterium tuberculosis.

PMID 36409105 · 2022

The ddn Trp20Stop mutation was found in isolates resistant to delamanid and pretomanid.

Mutation Information

Protein Change: W20*
Organisms: Mycobacterium tuberculosis
Confers Resistance To: delamanid|pretomanid
Validation Method: phenotypic drug susceptibility testing
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research