ResLit - Antimicrobial Resistance Gene & Mutation Database

GeneblaOXA-193

Nucleotide ChangeG-57T

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: up-regulation of bla OXA and high-level ß-lactam resistance
Resistance To: ampicillin
Organisms: Campylobacter coli, Campylobacter jejuni
Papers: 1

Paper Information1

Identification of knowledge gaps in whole-genome sequence analysis of multi-resistant thermotolerant Campylobacter spp.

PMID 38331708 · 2024

The promoter mutation at position −57 (G to T transversion) restores the Pribnow box, leading to up-regulation of bla OXA and high-level ß-lactam resistance.

Mutation Information

blaOXA-193: c.G-57T

Nucleotide Change: G-57T
Organisms: Campylobacter coli, Campylobacter jejuni
Confers Resistance To: ampicillin
Effect on Function: up-regulation of bla OXA and high-level ß-lactam resistance
Validation Method: whole genome sequencing and MIC testing
Source Database: Reslit

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