ResLit - Antimicrobial Resistance Gene & Mutation Database

Genepbp2x

penicillin-binding protein 2X

Protein ChangeL547V

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: meropenem
Organisms: Streptococcus mitis/oralis
Papers: 1

Paper Information1

Clinical isolates of Streptococcus mitis/oralis-related species with reduced carbapenem susceptibility, harboring amino acid substitutions in penicillin-binding proteins in Japan.

PMID 38415648 · 2024

Mutation Information

pbp2x: p.L547V

Protein Change: L547V
Organisms: Streptococcus mitis/oralis
Confers Resistance To: meropenem
Validation Method: whole genome sequencing and MIC testing
Source Database: Reslit

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