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Browse Mutations ompK36L359R

outer membrane protein

Protein ChangeL359R

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: deleterious
Resistance To: ceftazidime avibactam
Organisms: Klebsiella pneumoniae
Papers: 1

Paper Information1

1

Loss and gain of ceftazidime-avibactam susceptibility in a non-carbapenemase-producing K1-ST23 hypervirulent Klebsiella pneumoniae.

PMID 38697754 · 2024

The mutation leads to a deleterious effect on the function of OmpK36.

Mutation Information

ompK36: p.L359R

Protein Change: L359R
Organisms: Klebsiella pneumoniae
Confers Resistance To: ceftazidime avibactam
Effect on Function: deleterious
Validation Method: qRT-PCR and SDS-PAGE
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research