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Browse Mutations tufAQ124K

GenetufA

Protein ChangeQ124K

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: defective GTP/GDP interaction
Resistance To: kirromycin
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

A growth-defective kirromycin-resistant EF-Tu Escherichia coli mutant and a spontaneously evolved suppression of the defect.

PMID 7489913 · 1995

The mutation Q124K in the tufA gene leads to a growth-defective kirromycin-resistant phenotype.

Mutation Information

Protein Change: Q124K
Organisms: Escherichia coli
Confers Resistance To: kirromycin
Effect on Function: defective GTP/GDP interaction
Validation Method: genetic experiments and protein characterization
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research