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Browse Mutations oprD437delC

GeneoprD

porin

Nucleotide Change437delC

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: carbapenems, imipenem|meropenem|doripenem
Organisms: Pseudomonas aeruginosa
Papers: 1

Paper Information1

1

Persistence and Microevolution of Pseudomonas aeruginosa in the Cystic Fibrosis Lung: A Single-Patient Longitudinal Genomic Study.

PMID 30692969 · 2018

Deletion in oprD leads to carbapenem resistance

Mutation Information

oprD: c.437delC

Nucleotide Change: 437delC
Organisms: Pseudomonas aeruginosa
Confers Resistance To: carbapenemsimipenem|meropenem|doripenem
Validation Method: whole genome sequencing and comparison with susceptible isolates; whole genome sequencing and association with carbapenem resistance
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research